We have talked about how to disable certain regions using the Context module.
Drupal 7 – Disable certain regions by conditions using Context

But seems that it may not work for certain themes and regions. Luckily, there is another module called Delta which could be served as an alternative. Delta not only could disable the region but it could alter any theme settings for specific context condition. Let’s take a look now.

1. Download and install the Delta module.

 

2. Go to admin/appearance/delta and create a new delta. You will return to the delta listing page after save.

 

3. Click Configure and you will see a complete theme setting where you can disable any regions by setting the Zone Section to None.

 

4. Go to admin/structure/context and create a new context. Select the condition as u desire. Next, add the Delta reaction and pick the delta template u just create.

 

5. Save the context and check it out.

Done =)

Reference: Drupal module – Delta